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Nobese 15mg Tablet
Nobese 15mg Tablet is a medication that assists with weight-loss by altering neurotransmitters within the brain. Neurotransmitters are chemicals that are produced and released by nerves in order to communicate with other nerves. Released neurotransmitters may attach to other nerves or Nobese 15mg Tabletmay be taken up again by the nerves that release them, a process termed reuptake. Nobese 15mg Tablet blocks the reuptake of the neurotransmitters dopamine, norepinephrine, and serotonin. Blocking the reuptake of neurotransmitters alters the balance of neurotransmitters within the nerve cells and thereby affect nerve function and interaction. Patients taking Nobese 15mg Tablet may achieve a 5-10% reduction from their baseline weight. Additionally, sibutramine-assisted weight loss has been accompanied by improvement in blood lipids (e.g, cholesterol). Nobese 15mg Tablet was approved by the FDA in 1997. Nobese 15mg Tablet must be converted in the liver to its active form. This conversion is inhibited by ketoconazole (Nizoral), cimetidine (Tagamet) and erythromycin (Erytab, Eryc, Ilosone), and use of these drugs can result in decreased conversion and effectiveness of sibutramine. Several other drugs may have a similar effect.
This medicine helps in reducing the weight of obese patients with body mass index (BMI) ≥30 kg/m2 or ≥ 27 kg/m2 in the presence of risk factors such as diabetes, dyslipidemia, controlled hypertension, etc.
In general, sibutramine is well-tolerated. The most common side effects have been constipation, inability to sleep, headache, and dry mouth. Other side effects include abdominal pain, acne, rash, chest pain, anxiety, joint pain, back pain, excitation, depression, sweating, dizziness, drowsiness, changes in taste, irregular or painful menstrual periods, flu-like syndrome, increased cough, muscle pain, nausea, vomiting, neck pain, nervousness, palpitations, tingling of the extremities, sore throat, and sinus congestion.
When not use
This medicine is not recommended for use in patients with a known allergy to NOBESE 10mg Capsule 14s , or any other inactive ingredients present in the formulation.