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Zurig Tablets 40mg 20’s
Zurig Tablets 40mg 20’s (Febuxostat) is a non-purine selective inhibitor of xanthine oxidase. This Tabletis chemically described as 2-[3-cyano-4-(2-methylpropoxy) phenyl]-4-methylthiazole5-carboxylic acid. Zurig Tablets 40mg 20’s molecular formula is C16H16N2O3S. This Tablet (Febuxostat) is indicated for the chronic management of hyperuricemia in patients with gout. Treatment with this Tablet in patients with ischemic heart disease or congestive heart failure is not recommended.
After initiation of this Tablet, an increase in gout flares is frequently observed. This increase is due to reduction in serum uric acid levels resulting in mobilization of urate from tissue deposits. In order to prevent gout flares when this Tablet is initiated, concurrent prophylactic treatment with an NSAID or colchicine is recommended.
This Tablet is contraindicated in patients with: − Hypersensitivity to the active substance or to any of the excipients of the this Tablet . − Being treated with azathioprine, mercaptopurine or theophylline. − Asymptomatic hyperuricemia
Naproxen and other inhibitors of glucuronidation: This Tablet metabolism depends on UGT enzymes. Medicinal products that inhibit glucuronidation, such as NSAIDs and probenecid, could in theory affect the elimination of febuxostat. In healthy subjects concomitant use of febuxostat and naproxen 250mg BID was associated with an increase in febuxostat exposure.
Febuxostat can be co-administered with naproxen with no dose adjustment of febuxostat or naproxen being necessary. Patients with an overdose should be managed by symptomatic and supportive care.
Zurig 40mg Tablet (Febuxostat) is indicated for the chronic management of hyperuricemia in patients with gout.
Side Effects Of Zurig Tablets 40mg 20’s
- Increased liver enzymes
- Skin rash
- Gout flares
When Not To Use
This Tablet is contraindicated in patients with,
- Hypersensitivity to the active substance or to any of the excipients of the product.
- Being treated with azathioprine,
- mercaptopurine or theophylline.
- Asymptomatic hyperuricemia.
- Only use if recommended by your physician.
- Do not take higher than the dose that is prescribed.
- Avoid using it if your are allergic to febuxostat, or any other ingredients in this medication.
- Do not take it in conjunction with other medications such as azathioprine or theophylline.
- Inform your healthcare provider of any medical condition that you have had in the past or present, particularly if you’ve suffered from cancer stroke, heart disease, stroke liver disease, kidney disease or organ transplants.
Patients suffering from vascular disorders and heart problems like heart issues stroke, chest pain,
should use this medicine with caution.
Patients suffering from respiratory issues must be careful when taking this medication.