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Lenwin 125mg Syprup 60ml
Lenwin 125mg Syprup 60ml (Cephradine) is a first-generation cephalosporin antibacterial given orally and by parenteral route in the treatment of susceptible infections and in the prophylaxis of infections during surgical procedures. Chemically, Lenwin 125mg Syprup 60ml is (6R,7R)-7-[(R)-2-Amino-2-(1,4-cyclohexadien-1-yl)acetamido] -3- methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. The molecular formula of Lenwin 125mg Syprup 60ml is C16H19N3O4S. Cephradine should be used with caution in patients with known hypersensitivity to penicillins because of partial allergenicity between penicillins and the cephalosporins. – Caution should be exercised in patients with renal failure and dosage of Lenwin 125mg Syprup 60ml should be reduced. – False positive reaction for glucose in the urine may occur with Benedict’s or Fehling’s solution or with reagent tablets such as Clinitest following administration of cephradine. – Prolonged use with antibiotics may result in overgrowth of non susceptible microorganisms. Drug Interactions – Concomitant administration with loop diuretics may increase nephrotoxicity of cephalosporins. – Concomitant administration of probenecid raises serum concentrations of cephradine, by reducing renal clearance. For severe or chronic infection larger dose of up to 1g four times daily may be given. Administration should be continued for a minimum of 48- 72 hours after the patient becomes asymptomatic or evidence of bacterial eradication has been obtained. For infections caused by hemolytic strains of streptococci, a minimum of 10 days treatment is recommended to guard against the risk of rheumatic fever or glomerulo-nephritis.
This medicine is used to treat the infections of respiratory and gastrointestinal tracts, skin and soft tissue, bones and joints, septicaemia (blood poisoning), endocarditis (inflammation of the heart), urinary tract infections, and for preventing infections during surgeries.
The patients administered with this medicine may experience allergic reactions, gastrointestinal disturbances, and pseudomembranous colitis (inflammation of the lining of the large intestine).
When not use
The patients with allergy to any of the medicine’s components should avoid use of this medicine. Please consult your doctor before use.