Zantac Inj 50mg 5Ampx 2ml Ranitidine

For ulcer treatment, a night-time dose is especially important, as the increase in gastric and duodenal pH promotes healing overnight, when the stomach and duodenum are empty. Conversely, for treating acid reflux, smaller and more frequent doses are more effective.[medical citation needed]

Ranitidine was originally administered long-term for acid-reflux treatment, sometimes indefinitely. For some, though, proton pump inhibitors (PPIs) have taken over this role. In addition, in children, a fairly rapid tachyphylaxis can develop within six weeks of initiation of treatment, further limiting its potential for long-term.

People with Zollinger Ellison syndrome have been given high doses without any harm.