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Xeticam 500mg Tablet
Xeticam 500mg Tablet (Levetiracetam) is an analogue of piracetam. The chemical name of Xeticam 500mg Tablet, a single enantiomer, is (−)-(S)-α-ethyl-2-oxo-1-pyrrolidineacetamide.Xeticam 500mg Tablet molecular formula is C8H14N2O2. Renal impairment The administration of Xeticam 500mg Tablet to patients with renal impairment may require dose adjustment. In patients with severely impaired hepatic function, assessment of renal function is recommended before dose selection. Acute kidney injury The use of Xeticam 500mg Tablet has been very rarely associated with acute kidney injury, with a time to onset ranging from a few days to several months. Blood cell counts Rare cases of decreased blood cell counts (neutropenia, agranulocytosis, leucopenia, thrombocytopenia and pancytopenia) have been described in association with Xeticam 500mg Tablet administration, generally at the beginning of the treatment. Complete blood cell counts are advised in patients experiencing significant weakness, pyrexia, recurrent infections or coagulation disorders.
Probenecid Renal clearance of ucb L057 in the presence of probenecid decreased 60%, probably related to competitive inhibition of tubular secretion of ucb.
In the treatment of partial onset seizures with or without secondary generalization in adults and adolescents from 16 years of age with newly diagnosed epilepsy. Adjunctive Therapy: • in the treatment of partial onset seizures with or without secondary generalization in adults, adolescents and children 6 years of age . • in the treatment of myoclonic seizures in adults and adolescents from 12 years of age with Juvenile Myoclonic Epilepsy. • in the treatment of primary generalized tonic-clonic seizures in adults and adolescents from 6 years of age with Idiopathic Generalized Epilepsy.
Side effect :
Very common: Nasopharyngitis, somnolence and headache. Common: Anorexia, depression, hostility/aggression, anxiety, insomnia, nervousness/irritability, convulsion, balance disorder, dizziness, lethargy, tremor, vertigo, cough, abdominal pain, diarrhoea, dyspepsia, vomiting, nausea, rash and asthenia/fatigue. Uncommon: Thrombocytopenia
When not use :
Xeticam 500mg Tablet is containdiacted in patients who are hypersensitive to the active substance or other pyrrolidone derivatives or to any excipient of the product