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Vanit 50mg Tablet
Vanit 50mg Tablet (Dexibuprofen), [S(+)-Ibuprofen], is considered as the pharmacologically active enantiomer of ibuprofen. Racemic ibuprofen is a non-steroidal substance that possesses anti-inflammatory and analgesic effects. Chemically, Vanit 50mg Tablet is described as S(+)-2-(4-Isobutylphenyl)propionic acid.Vanit 50mg Tablet molecular formula is C13H18O2. The use of Vanit 50mg Tablet with concomitant NSAIDs including cyclooxygenase-2 selective inhibitors should be avoided. Care is recommended in conditions that predispose patients to the gastrointestinal adverse effects of NSAIDs. These patients should be closely monitored for digestive disturbances, especially gastrointestinal bleeding, perforation & ulceration. – Appropriate monitoring and advice are required for patients with a history of hypertension and/or mild to moderate congestive heart failure as fluid retention and edema have been reported in association with NSAID therapy. Patients with uncontrolled hypertension, congestive heart failure, established ischemic heart disease, peripheral arterial disease, and/or cerebrovascular disease should only be treated with Vanit 50mg Tablet after careful consideration.
Anticoagulants: NSAIDs may enhance the effect of anti-coagulants, such as warfarin. Blood coagulation tests (INR, bleeding time) should be performed during the initiation of dexibuprofen treatment and the dosage of the anticoagulant should be adjusted if necessary. Methotrexate used at doses of 15 mg/week or more: The concomitant use of dexibuprofen and high dose treatment with methotrexate within 24 hours of each other is not recommended because it may increase the potential for methotrexate toxicity
This medicine is used to provide relief from mild to moderate pain experienced in osteoarthritis (bone and joint disease), dysmenorrhoea (painful periods) and for dental pain
Side effect :
This medicine can cause stomach upset and abdominal pain, dizziness, drowsiness, headache and vertigo (loss of balance). Skin rash is also a side effect that requires immediate stopping of therapy.
When not use :
This medicine must not be used by patients with active stomach ulcers and bleeding, severe liver and kidney disease, allergy to aspirin/anti-inflammatory drugs, Congestive heart failure and Blood clotting disorders.