Glucovance Tab 5mg/500mg 2×15’s
₨149.73
Pack Size: 2X15’s
Composition: Glibenclamide 5mg , Metformin 500mg
Pharmaceutical form: Tablet
Brand Name: Martin Dow
Availability: In stock
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Description
Glucovance Tab 5mg/500mg 2×15’s
Glucovance Tab 5mg/500mg 2×15’s is used to control blood glucose levels (the amount of sugar in the blood) in adults with type II diabetes mellitus. This type of diabetes is also known as non-insulin dependent diabetes mellitus (NIDDM) or maturity onset diabetes.
For patients not adequately controlled on either glyburide (or another sulfonylurea) or metformin alone, the recommended starting dose of GLUCOVANCE is 2.5 mg/500 mg or 5 mg/500 mg twice daily with the morning and evening meals.
Glyburide use should be avoided in patients with severe kidney impairment as defined by a GFR of less than 60 mL/min (CKD stage 3 and below). Because 50 percent of the glyburide is excreted by the kidneys, the drug can build up in people with CKD, causing low blood sugar levels.
GLUCOVANCE is available for oral administration in tablets containing 1.25 mg or 5 mg/500 glyburide with 250 mg metformin hydrochloride, 2.5 mg glyburide with 500 mg metformin hydrochloride, and 5 mg glyburide with 500 mg metformin hydrochloride. In addition, each tablet contains the following inactive ingredients: microcrystalline cellulose, povidone, croscarmellose sodium, and magnesium stearate. The tablets are film coated, which provides color differentiation.
Uses
Glucovance is used to control blood glucose levels (the amount of sugar in the blood) in adults with type II diabetes mellitus. This type of diabetes is also known as non-insulin dependent diabetes mellitus (NIDDM) or maturity onset diabetes.
Side Effects
In double-blind clinical trials involving GLUCOVANCE as initial therapy or as second-line therapy, a total of 642 patients received GLUCOVANCE, 312 received metformin therapy, 324 received glyburide therapy, and 161 received placebo. The percent of patients reporting events and types of adverse events reported in clinical trials of GLUCOVANCE (all strengths) as initial therapy and second-line therapy are listed in Table 6.
When Not To Use
Glucovance (Glyburide and Metformin) may treat, side effects, dosage, drug interactions … GLUCOVANCE 5 mg/500 mg should not be used as initial therapy due to an … GLUCOVANCE 2.5 mg/500 mg tablet is a pale orange, capsule-shaped.
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