Getofin 250mg Im Injection
Getofin 250mg Im Injection is a sterile, semisynthetic, broad-spectrum cephalosporin antibiotic for intravenous or intramuscular administration. Chemically Ceftriaxone sodium is (6R,7R)-7-[2-(2-Amino-4-thiazolyl)glyoxylamido]-8-oxo-3-[[(1,2,5,6-tetrahydro-2- methyl-5,6-dioxo-as triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2- carboxylic acid, 72-(Z)-(O-methyloxime), disodium salt, sesquaterhydrate. The molecular formula of Getofin 250mg Im Injection is C18H16N8Na2O7S3•3.5H2O. Getofin 250mg Im Injection may be administered by deep intramuscular injection, slow intravenous injection, or as a slow intravenous infusion, after reconstitution of the solution according to the given directions . General In patients of any age ceftriaxone must not be mixed or administered simultaneous ly with any calcium-containing IV solutions , even via different infusion lines or at different infusion s ites. However, in patients older than 28 days of age ceftriaxone and calcium-containing solutions may be administered sequentially one after another if infusion lines at different sites are used, or if the infusion lines are replaced or thoroughly flushed between infusions with physiological salt-solution to avoid precipitation.
Getofin 250mg Im Injection is indicated for the treatment of the following infections due to susceptible organisms. Such infections include: Lower respiratory tract infections Acute bacterial otitis media Skin and skin structure infections Urinary tract infections (complicated and uncomplicated) Uncomplicated gonorrhea (cervical/urethral and rectal) Pelvic inflammatory disease Bacterial septicemia Bone and joint infections Intra-abdominal infections Meningitis. Surgical prophylaxis of infections. Infections in neutrope
Diarrhea, nausea and vomiting.Rare Mycosis of the genital tract, neutropenia, leucopenia, eosinophilia, thrombocytopenia, anaemia (including haemolytic anaemia), slight prolongation of prothrombin time, anaphy lactic (e.g. bronchospasm) and anaphy lactoid reactions, headache, dizziness, Increase in serum liver enzymes , rigors and pyrexia.
When not use
Getofin 250mg Im Injection is contraindicated in patients with: – Hypersensitivity to ceftriaxone or to any of the cephalosporins. – Previous immediate and/or severe hypersensitivity reaction to penicillin or to any other type of beta-lactam drug. – Premature newborns up to a corrected age of 41 weeks .